Overview
VAC4EU Network
The DSRU is a very active member of Vaccine monitoring collaboration for Europe (VAC4EU), a European collaborative research network for monitoring the safety and effectiveness of vaccines.
We joined VAC4EU during the Covid pandemic in order to be able to collaborate with European partners to monitor the safety of vaccines across Europe. Our experienced epidemiology team now has more than 10 vaccine safety studies completed or in progress with VAC4EU on Covid and non-Covid vaccines.
Find out more about these safety studies here: https://www.dsru.org/dsrunews/electronic-health-record-data/
About VAC4EU
VAC4EU is a not-for-profit international association of 28 members which form a well-characterised public study network. The network has developed a streamlined study pipeline for the generation of real-world evidence (RWE) from real-world data (RWD).
This standardised pipeline forms the basis for the regulatory-grade vaccine studies carried out by study teams, informing on vaccine safety and effectiveness across Europe. The network consists of 14 data sources which provide a range of different types of data for RWE studies.
Evidence generated from VAC4EU’s studies helps regulators and public health bodies make timely, informed decisions about vaccine safety and effectiveness.
Examples of vaccine safety studies conducted by the DSRU as a VAC4EU member include:
- Clinical course, outcomes and risk factors of myocarditis and pericarditis following administration of Moderna vaccines targeting SARS-CoV-2
- Post-Authorization Safety Study (PASS) among recipients of the Pfizer-BioNTech COVID-19 (COMIRNATY®)
- A post-authorisation/post-marketing observational study to evaluate the association between exposure to AZD1222 and safety concerns using existing secondary health data sources (COVID-19)
