Publications

Reasons for and time to discontinuation of rimonabant therapy: a Modified Prescription-Event Monitoring Study

• Author

  Marjolein J C Willemen Aukje K Mantel-Teeuwisse Yvonne Buggy Deborah Layton Sabine M J M Straus Hubert G M Leufkens Toine C G Egberts

  Marjolein Willemen, Aukje Mantel-Teeuwise, Yvonne Buggy, Deborah Layton, Sabine Straus, Hubert Leufkens, Toine Egberts

• Cite

  Drug Saf. 2012 Dec 1;35(12):1147-58

Patient versus Healthcare Professional Spontaneous Adverse Drug Reaction Reporting: A systematic review

• Author

  Jackie Inch Margaret C Watson Stella Anakwe-Umeh

  Jackie Inch, Margaret Watson, Stella Anakwe-Umeh

• Cite

  Drug Saf. 2012 Oct 1;35(10):807-18

Common variation in the NOS1AP gene is associated with drug-induced QT prolongation and ventricular arrhythmia

• Author

  Yalda Jamshidi Ilya M Nolte Chrysoula Dalageorgou Dongling Zheng Toby Johnson Rachel Bastiaenen Suzanne Ruddy Daniel Talbott Kris J Norris Harold Snieder Alfred L George Vanessa Marshall Saad Shakir Prince J Kannankeril Patricia B Munroe A John Camm Steve Jeffery Dan M Roden Elijah R Behr

  Yalda Jamshidi, Ilya Nolte, Chrysoula Dalageorgou, Dongling Zheng, Toby Johnson, Rachel Bastiaenen, Suzanne Ruddy, Daniel Talbott, Kris Norris, Harold Snieder, Alfred George, Vanessa Marshall, Saad Shakir, Prince Kannankeril, Patricia Munroe, John Camm, Steve Jeffery, Dan Roden, Elijah Behr

• Cite

  Journal of the American College of Cardiology. 2012 Aug 28;60(9):841-50

Influenza H1N1 (swine flu) vaccination: a safety surveillance feasibility study using self-reporting of serious adverse events and pregnancy outcomes

• Author

  Isla S Mackenzie Thomas M MacDonald Saad Shakir Moira Dryburgh Brian J Mantay Patrick McDonnell Deborah Layton

  Isla Mackenzie, Thomas MacDonald, Saad Shakir, Moira Dryburgh, Brian Mantay, Patrick McDonnell, Deborah Layton

• Cite

  British Journal of Clinical Pharmacology, May 2012; 73(5):801-11

A large candidate gene survey identifies the KCNE1 D85N polymorphism as a possible modulator of drug-induced torsades de pointes Kääb

• Author

  Stefan Kääb Dana C Crawford Moritz F Sinner Elijah R Behr Prince J Kannankeril Arthur A M Wilde Connie R Bezzina Eric Schulze-Bahr Pascale Guicheney Nanette H Bishopric Robert J Myerburg Jean-Jacques Schott Arne Pfeufer Britt-Maria Beckmann Eimo Martens Taifang Zhang Birgit Stallmeyer Sven Zumhagen Isabelle Denjoy Abdenasser Bardai Isabelle C Van Gelder Yalda Jamshidi Chrysoula Dalageorgou Vanessa Marshall Steve Jeffery Saad Shakir A John Camm Gerhard Steinbeck Siegfried Perz Peter Lichtner Thomas Meitinger Annette Peters H-Erich Wichmann Christiana Ingram Yuki Bradford Shannon Carter Kris Norris Marylyn D Ritchie Alfred L George Jr Dan M Roden

  Stefan Kääb, Dana Crawford, Moritz F Sinner, Elijah Behr, Prince Kannankeril, Arthur Wilde, Connie Bezzina, Eric Schulze-Bahr, Pascale Guicheney, Nanette Bishopric, Robert J Myerburg, Jean-Jacques Schott, Arne Pfeufer, Britt-Maria Beckmann, Eimo Martens, Taifang Zhang, Birgit Stallmeyer, Sven Zumhagen, Isabelle Denjoy, Abdenasser Bardai, Isabelle Van Gelder, Yalda Jamshidi, Chrysoula Dalageorgou, Vanessa Marshall, Steve Jeffery, Saad Shakir, John Camm, Gerhard Steinbeck, Siegfried Perz, Peter Lichtner, Thomas Meitinger, Annette Peters, H-Erich Wichmann, Christiana Ingram, Yuki Bradford, Shannon Carter, Kris Norris, Marylyn Ritchie, Alfred George, Dan Roden

• Cite

  Circulation: Cardiovascular Genetics. 2012 Feb 1;5(1):91-9

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Modified Prescription-Event Monitoring Studies: a tool for Pharmacovigilance and Risk Management

• Author

  Deborah Layton Lorna Hazell Saad A W Shakir

  Deborah Layton, Lorna Hazell, Saad Shakir

• Cite

  Drug Safety. 2011 December 1;34(12)

Examining the utilization and tolerability of the non-sedating antihistamine levocetirizine in England using prescription-event monitoring data

• Author

  Deborah Layton Vicki Osborne Anna Gilchrist Saad A W Shakir

  Deborah Layton, Vicki Osborne, Anna Gilchrist, Saad Shakir

• Cite

  Drug Safety. 2011 Dec 1;34(12):1177-89

Risk of depressive episodes with rimonabant: a before and after modified prescription-event monitoring study conducted in England

• Author

  Yvonne Buggy Victoria Cornelius Lynda Wilton Saad A W Shakir

  Yvonne Buggy, Victoria Cornelius, Lynda Wilton, Saad Shakir

• Cite

  Drug Safety. 2011 Jun 1;34(6):501-9

Paediatric post-marketing pharmacovigilance: comparison of the adverse event profile of vigabatrin prescribed to children and adults

• Author

  Beate Aurich-Barrera Lynda Wilton David Brown Saad Shakir

  Beate Aurich-Barrera, Lynda Wilton, David Brown, Saad Shakir

• Cite

  Pharmacoepidemiology and Drug Safety. 2011 Jun;20(6):608-18

New postgraduate qualifications in pharmacovigilance from the Drug Safety Research Unit in the UK

• Author

  Elizabeth Lynn Deborah Layton Saad Shakir

  Elizabeth Lynn, Deborah Layton, Saad Shakir

• Cite

  Drug Safety. 2011 Jan 1;34(1):89-91

Hypoglycaemia with pioglitazone: analysis of data from the Prescription-Event Monitoring study.

• Author

  Veronika Vlckova Victoria Cornelius Rachna Kasliwal Lynda Wilton Saad Shakir

  Veronika Vlckova, Victoria Cornelius, Rachna Kasliwal, Lynda Wilton, Saad Shakir

• Cite

  J Eval Clin Pract. 2010 Dec;16(6):1124-8

Paediatric postmarketing pharmacovigilance using prescription-event monitoring: a comparison of the adverse event profiles of lamotrigine prescribed in children and adults in England

• Author

  Beate Aurich-Barrera Lynda Wilton David Brown Saad Shakir

  Beate Aurich-Barrera, Lynda Wilton, David Brown, Saad Shakir

• Cite

  Drug Safety. 2010 Sep 1;33(9):751-63

Adverse drug reaction reporting in the UK: A retrospective observational comparison of Yellow Card Reports submitted by patients and healthcare professionals

• Author

  David J McLernon Christine M Bond Philip C Hannaford Margaret C Watson Amanda J Lee Lorna Hazell Anthony Avery

  David McLernon, Christine Bond, Philip Hannaford, Margaret Watson, Amanda Lee, Lorna Hazell, Anthony Avery

• Cite

  Drug Safety. 2010 Sep 1;33(9):775-88

Incidence of venous thromboembolism in users of strontium ranelate: an analysis of data from a prescription-event monitoring study in England

• Author

  Vicki Osborne Deborah Layton Michael Perrio Lynda Wilton Saad A W Shakir

  Vicki Osborne, Deborah Layton, Michael Perrio, Lynda Wilton, Saad Shakir

• Cite

  Drug Safety. 2010 Jul 1;33(7):579-91

Safety profile of oxcarbazepine: results from a prescription-event monitoring study

• Author

  Yvonne Buggy Deborah Layton Carole Fogg Saad A W Shakir

  Yvonne Buggy, Deborah Layton, Carole Fogg, Saad Shakir

• Cite

  Epilepsia. 2010 May;51(5):818-29

Drug Utilization of Intrinsa (Testosterone Patch) In England: Interim analysis of a Prescription-Event Monitoring Study to support Risk Management

• Author

  Vicki Osborne Lorna Hazell Deborah Layton Saad A W Shakir

  Vicki Osborne, Lorna Hazell, Deborah Layton, Saad Shakir

• Cite

  Drug Saf. 2010 Mar 1;33(3):213-21

Systematic reviews of adverse effects of drug interventions: a survey of their conduct and reporting quality Cornelius

• Author

  V R Cornelius M J Perrio S A W Shakir L A Smith

  Victoria Cornelius, Michael Perrio, Saad Shakir, Leslie Smith

• Cite

  Pharmacoepidemiol Drug Saf. 2009 Dec;18(12)

Strontium ranelate as a cause of acute renal failure and dress syndrome

• Author

  Deepa Iyer Yvonne Buggy Katherine O-Reilly Martin Searle

  Deepa Iyer, Yvonne Buggy, Katherine O-Reilly, Martin Searle

• Cite

  Nephrology (Carlton). 2009 Sep;14(6):624

The safety profile of tadalafil as prescribed in general practice in England: results from a prescription-event monitoring study involving 16 129 patients.

• Author

  Lorna Hazell Victoria Cornelius Lynda V Wilton Saad A W Shakir

  Lorna Hazell, Victoria Cornelius, Lynda Wilton, Saad Shakir

• Cite

  BJU Int. 2009 Feb;103(4):506-14

Pattern of drug utilisation for treatment of uncomplicated malaria in urban Ghana following national treatment policy change to artemisinin-combination therapy

• Author

  Alexander N O Dodoo Carole Fogg Alex Asiimwe Edmund T Nartey Augustina Kodua Ofori Tenkorang David Ofori-Adjei

  Alexander Dodoo, Carole Fogg, Alex Asiimwe, Edmund Nartey, Augustina Kodua, Ofori Tenkorang, David Ofori-Adjei

• Cite

  Malar J. 2009 Jan 5;8:2

Safety Profile of Varenicline as used in General Practice in England: Interim Results from a Prescription-Event Monitoring Study

• Author

  Rachna Kasliwal Lynda V Wilton Saad A W Shakir

  Rachna Kasliwal, Lynda Wilton, Saad Shakir

• Cite

  Drug Safety. 2009;32(6):499-507

Hypoglycaemia with anti-diabetic drugs: Results from Prescription-Event Monitoring cohorts of rosiglitazone, pioglitazone, nateglinide and repaglinide

• Author

  Veronika Vlckova Victoria Cornelius Rachna Kasliwal Lynda Wilton Saad A W Shakir

  Veronika Vlckova, Victoria Cornelius, Rachna Kasliwal, Lynda Wilton, Saad Shakir

• Cite

  Drug Safety. 2009;32(5):409-18

Risk management and outcomes of adverse events to Pioglitazone in Primary Care in the UK; an observational study

• Author

  Carole Fogg Rachna Kasliwal Saad A W Shakir

  Carole Fogg, Rachna Kasliwal, Saad Shakir

• Cite

  Drug Safety. 2009;32(3):229-37

Neuraminidase inhibitors: widespread use for influenza may reveal more adverse effects

• Author

  Layton D Cox A

  Debabrata Roy, Anthony Cox

• Cite

  The Pharmaceutical Journal. January 2009

Use and risk management of Carvedilol for the treatment of heart failure in the community in England: results from a modified prescription-event monitoring study

• Author

  Beate Aurich-Barrera Lynda V Wilton Saad A W Shakir

  Beate Aurich-Barrera, Lynda Wilton, Saad Shakir

• Cite

  Drug Safety. 2009;32(1):43-54.