Past studies
The following is a list of medicines we have studied at the DSRU using various methodologies including Prescription Event Monitoring (PEM), Modified Prescription Event Monitoring (M-PEM) and Specialist Cohort Event Monitoring (SCEM). Some studies were for regulatory and internal purposes only and therefore have not been published. They will not be found when searching for DSRU publications.
PEM studies (in primary care)
| Generic drug name |
Brand Name |
Group |
Cohort |
| Cisapride |
PREPULSID |
Antispasmodic |
13234 |
| Famotidine |
PEPCID |
H2-antagonist |
9500 |
| Nizatidine |
AXID |
H2-antagonist |
7782 |
| Misoprostol |
CYTOTEC |
Prostaglandin analogue |
13775 |
| Lansoprazole |
ZOTON |
Proton pump inhibitor |
17329 |
| Omeprazole |
LOSEC |
Proton pump inhibitor |
16204 |
| Pantoprazole |
PROTIUM |
Proton pump inhibitor |
11541 |
| Esomeprazole |
NEXIUM |
Proton pump inhibitor |
11595 |
| Betaxolol |
KERLONE |
Beta-blocker |
1531 |
| Doxazosin |
CARDURA |
Alpha-blocker |
8482 |
| Enalapril |
INNOVACE |
ACE-inhibitor |
15361 |
| Lisinopril |
ZESTRIL+CARACE |
ACE-inhibitor |
12438 |
| Perindopril |
COVERSYL |
ACE-inhibitor |
9089 |
| Ramipril |
TRITACE |
ACE-inhibitor |
1371 |
| Irbesartan |
APROVEL |
Antihypertensive |
14398 |
| Losartan |
COZAAR |
Antihypertensive |
14522 |
| Valsartan |
DIOVAN |
Antihypertensive |
12881 |
| Amlodipine |
ISTIN |
Ca-antagonist |
12969 |
| Diltiazem |
TILDIEM |
Ca-antagonist |
10112 |
| Isradipine |
PRESCAL |
Ca-antagonist |
3679 |
| Mibefradil |
POSICOR |
Ca-antagonist |
3085 |
| Nicardipine |
CARDENE |
Ca-antagonist |
10910 |
| Nicorandil |
IKOREL |
K-channel activator |
13620 |
| Xamoterol |
CORWIN |
Inotropic |
5373 |
| Fluvastatin |
LESCOL |
Lipid-lowering |
7542 |
| Bambuterol |
BAMBEC |
Beta2 agonist |
8098 |
| Eformoterol |
FORADIL |
Beta2 agonist |
5777 |
| Salmeterol |
SEREVENT |
Beta2 agonist |
15407 |
| Nedocromil |
TILADE |
Asthma |
12294 |
| Montelukast |
SINGULAIR |
Leukotriene |
15612 |
| Zafirlukast |
ACCOLATE |
Leukotriene |
7976 |
| Acrivastine |
SEMPREX |
Antihistamine |
7863 |
| Cetirizine |
ZIRTEK |
Antihistamine |
9554 |
| Fexofenadine |
TELFAST |
Antihistamine |
16638 |
| Loratadine |
CLARITYN |
Antihistamine |
9308 |
| Zolpidem |
STILNOCT |
Hypnotic |
13460 |
| Zopiclone |
ZIMOVANE |
Hypnotic |
11543 |
| Buspirone |
BUSPAR |
Anxiolytic |
11113 |
| Olanzapine |
ZYPREXA |
Antipsychotic |
8858 |
| Risperidone |
RISPERDAL |
Antipsychotic |
7684 |
| Sertindole |
SERDOLECT |
Antipsychotic |
436 |
| Moclobemide |
MANERIX |
MAOI |
10835 |
| Fluoxetine |
PROZAC |
SSRI |
12692 |
| Fluvoxamine |
FAVERIN |
SSRI |
10983 |
| Paroxetine |
SEROXAT |
SSRI |
13741 |
| Sertraline |
LUSTRAL |
SSRI |
12734 |
| Mirtazapine |
ZISPIN |
Antidepressant |
13554 |
| Nefazodone |
DUTONIN |
Antidepressant |
11834 |
| Venlafaxine |
EFEXOR |
Antidepressant |
12642 |
| Orlistat |
XENICAL |
Anti-obesity |
16022 |
| Tramadol |
ZYDOL |
Analgesic |
10532 |
| Sumatriptan |
IMIGRAN |
Antimigraine |
14928 |
| Lamotrigine |
LAMICTAL |
Anti-epileptic |
11316 |
| Vigabatrin |
SABRIL |
Anti-epileptic |
10178 |
| Gabapentin |
NEURONTIN |
Anti-epileptic |
3100 |
| Donepezil |
ARICEPT |
Alzheimer’s treatment |
1762 |
| Cefixime |
SUPRAX |
Cephalosporin |
11250 |
| Azithromycin |
ZITHROMAX |
Macrolide |
11275 |
| Ciprofloxacin |
CIPROXIN |
Quinolone |
11477 |
| Enoxacin |
COMPRECIN |
Quinolone |
2790 |
| Norfloxacin |
UTINOR |
Quinolone |
11110 |
| Ofloxacin |
TARIVID |
Quinolone |
11033 |
| Fosfomycin |
MONURIL |
Antibacterial |
3363 |
| Fluconazole |
DIFLUCAN |
Antifungal |
15015 |
| Itraconazole |
SPORANOX |
Antifungal |
13645 |
| Aciclovir |
ZOVIRAX |
Antiviral |
11051 |
| Famciclovir |
FAMVIR |
Antiviral |
14169 |
| Valaciclovir |
VALTREX |
Antiviral |
12804 |
| Acarbose |
GLUCOBAY |
Antidiabetic |
13655 |
| Repaglinide |
NOVONORM |
Antidiabetic |
5729 |
| Troglitazone |
ROMOZIN |
Antidiabetic |
1344 |
| Rosiglitazone |
AVANDIA |
Antidiabetic |
14418 |
| Pioglitazone |
ACTOS |
Antidiabetic |
12772 |
| Nateglinide |
STARLIX |
Oral antidiabetic |
4557 |
| Raloxifene |
EVISTA |
Osteoporosis |
13987 |
| Risedronate |
ACTONEL |
PM Osteoporosis |
13643 |
| Finasteride |
PROSCAR |
Prostate treatment |
14772 |
| Alendronate |
FOSAMAX |
Biphosphonate |
11916 |
| Tamsulosin |
FLOMAX |
MR Alpha-blocker |
12484 |
| Terodiline |
TEROLIN |
Anticholinergic |
12444 |
| Tolterodine |
DETRUSITOL |
Anticholinergic |
14526 |
| Sildenafil |
VIAGRA |
Anti-impotence |
22473 |
| Apomorphine |
UPRIMA |
Anti-impotence |
11185 |
| Bupropion |
ZYBAN |
Anti smoking aid |
11735 |
| Celecoxib |
CELEBREX |
NSAID |
17458 |
| Etodolac |
LODINE |
NSAID |
9091 |
| Meloxicam |
MOBIC |
NSAID |
19087 |
| Nabumetone |
RELIFEX |
NSAID |
10444 |
| Rofecoxib |
VIOXX |
NSAID |
15268 |
| Tenoxicam |
MOBIFLEX |
NSAID |
10882 |
| Tiotropium |
SPIRIVA |
Antimuscarinic Bronchodilator |
13892 |
| Rosuvastatin |
CRESTOR |
Lipid lowering |
11680 |
| Oxcarbazepine |
TRILEPTAL |
Anti-epileptic |
2243 |
| Desloratadine |
NEOCLARITYN |
Antihistamine |
11828 |
| Nateglinide |
STARLIX |
Anti diabetic |
4557 |
| Sibutramine |
REDUCTIL |
Anti-obesity |
12336 |
| Tadalafil |
CIALIS |
Anti-impotence |
6266 (cohort 1)
16129 (cohort 2) |
| Quetiapine |
SEROQUEL |
Anti-psychotic |
1728 |
| Levocetirizine |
XYZAL |
Anti histamine |
12876 |
| Tacrolimus |
PROTOPIC |
Topical immunomodulator |
12895 |
| Vardenafil |
LEVITRA |
Anti-impotence |
15656 |
| Aripiprazole |
ABILIFY |
Anti-psychotic |
4955 |
| Testosterone patch |
INSTRINSA |
Hormone |
3073 |
| Aliskiren |
RASILEZ |
Renin inhibitor |
6385 |
| Strontium ranelate |
PROTELOS |
Bone disease |
10865 |
| Etoricoxib |
ARCOXIA |
NSAID |
12665 |
| Ibandronic acid |
BONVIVA |
Osteoporosis |
11034 |
| Solifenacin |
VESICARE |
Urinary incontinence |
11341 |
| Deferasirox |
EXJADE |
Iron chelation |
122 |
| Duloxetine |
CYMBALTA/ YENTREVE |
Antidepressant/ Urinary incontinence |
19485 |
M-PEM Studies (in primary care)
| Generic drug name |
Brand Name |
Group |
Cohort |
| Atomoxetine |
STRATTERA |
ADHD treatment |
5079 |
| Budesonide |
PULMICORT |
Corticosteroid |
10408 |
| Carvedilol |
EUCARDIC |
Beta blocker |
1666 |
| Fentanyl |
EFFENTORA |
Opioid analgesic |
556 |
| Fentanyl |
PECFENT |
Opioid analgesic |
63 |
| Fluticasone |
FLIXOTIDE EVOHALER |
Corticosteroid |
13413 |
| Fluticasone |
SERETIDE EVOHALER |
Corticosteroid |
13464 |
| Ipratopium bromide |
ATROVENT |
Antimuscarinic Bronchodilator |
13211 |
| Lumiracoxib |
PREXIGE |
NSAID |
285 |
| Modafanil |
PROVIGIL |
ADHD treatment |
2092 |
| Travoprost |
TRAVATAN |
Prostaglandin analogue |
3528 |
| Varenicline |
CHAMPIX |
Nicotinic receptor partial agonist |
12135 |
| Ivabridine |
PROCORALAN |
Antianginal |
4624 |
SCEM Studies (in secondary care)
| Generic drug name |
Brand Name |
|
| Quetiapine XL |
Seroquel XL |
(OASIS Study) |
Vaccine Studies
| Generic drug name |
Brand Name |
|
| Seasonal influenza vaccine |
Fluenz Tetra |
Flu Vaccine Feedback Study |
